Treating Endothelial Dysfunction

(Protecting the inner lining of your arteries for better heart health)

What is Endothelial Dysfunction?

The endothelium is the thin layer of cells lining the inside of your blood vessels. It plays a critical role in keeping vessels flexible and open, controlling blood clotting and inflammation, and regulating blood flow. Understanding endothelial dysfunction treatment starts with knowing how this important layer works.

When the endothelium becomes damaged or doesn’t work properly (dysfunction), it contributes to:
Atherosclerosis (plaque buildup)
High blood pressure
Heart attack & stroke

What Can You Do?

How is It Detected?

There is no single routine test, but it can be assessed in research or specialized clinics using methods that help guide endothelial dysfunction treatment.

Flow-mediated dilation (FMD) of the brachial artery

EndoPAT (peripheral arterial tonometry)

Coronary reactivity testing

How to Improve Endothelial Function

The good news: it’s reversible with healthy changes and endothelial dysfunction treatment!

Lifestyle Changes

Stop smoking — one of the most powerful ways to restore endothelial health

Eat a Mediterranean or DASH diet — rich in fruits, vegetables, whole grains, and healthy fats

Exercise regularly — improves vessel flexibility and nitric oxide production

Manage stress & sleep well

Medications (if needed)

Certain medications improve endothelial function, especially in people at high risk:

Statins — lower LDL & improve endothelial health

ACE inhibitors or ARBs — lower BP & reduce vascular inflammation

Beta-blockers — sometimes used to reduce vascular stress

Antioxidants & supplements — (evidence is limited; always discuss with a provider)

Takeaway

Endothelial dysfunction is an early and reversible step toward heart disease. Healthy lifestyle changes, along with medical management when appropriate, can restore endothelial health and lower cardiovascular risk. Schedule a checkup at Insight Heart Health to discuss personalized endothelial dysfunction treatment and take proactive steps today.

Dr. Simona Campa
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